Pandemic Planning

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PANDEMIC FLU FAQs

Who is most at risk during a pandemic flu?

Many age groups are likely to be seriously affected by a pandemic flu. The people at greatest risk of hospitalization and death—as seen during the last two pandemics in 1957 and 1968 and during annual seasonal flu—will be:

  • infants
  • the elderly
  • individuals with underlying health conditions

However, in the 1918 pandemic, most deaths occurred in young adults. Few, if any, people would have immunity to a pandemic flu virus.[15]

next: What are the expected levels of illness and mortality from a pandemic flu?

 
Important Safety Information About RELENZA

RELENZA IS NOT RECOMMENDED FOR TREATMENT OR PROPHYLAXIS OF INFLUENZA IN INDIVIDUALS WITH UNDERLYING AIRWAY DISEASE (SUCH AS ASTHMA OR CHRONIC OBSTRUCTIVE PULMONARY DISEASE).
  • Serious cases of bronchospasm, including fatalities, have been reported during treatment with RELENZA in patients with and without underlying airway disease. Many of these cases were reported during postmarketing, and causality was difficult to assess
  • RELENZA SHOULD BE DISCONTINUED IN ANY PATIENT WHO DEVELOPS BRONCHOSPASM OR DECLINE IN RESPIRATORY FUNCTION; immediate treatment and hospitalization may be required
  • Safety and efficacy have not been demonstrated in patients with high-risk underlying medical conditions
  • Patients should be instructed in the use of the delivery system. Instructions should include a demonstration whenever possible
  • If treatment with RELENZA is considered for a patient with underlying airway disease, the potential risks and benefits should be carefully weighed. If a decision is made to prescribe RELENZA for such a patient, this should be done only under conditions of careful monitoring of respiratory function, close observation, and appropriate supportive care including availability of fast-acting bronchodilators
  • Common adverse events in treatment and prophylaxis studies with RELENZA were nausea, diarrhea, sinusitis, viral respiratory infections, headaches, nasal signs and symptoms. The incidence of these adverse events was similar in both groups for RELENZA and placebo-treated groups
  • Please see complete Prescribing Information for RELENZA


Few—if any—people
would have immunity
to a pandemic flu virus
[15]


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